Search results for "ISM [X-ray]"

showing 10 items of 1056 documents

Sur le texte du Peri phygees de Favorinos d'Arles

2015

Vengono proposte una serie di nuovi emendamenti al testo del discorso "Sull´ esilio" di Favorino, tramandato da un papiro Vaticano.

textual criticism papyrology
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Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives

2014

A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…

thiopheneVLAK protocolStereochemistryIn silicoCellAntineoplastic AgentsMechanism of actionHeLa CellHeLaAntineoplastic AgentStructure-Activity Relationship3-Benzoylamino-5-imidazol-4-yl-benzo[b]Settore BIO/10 - BiochimicaDrug DiscoverymedicineHumansMoietyComputer SimulationMitosisCell ProliferationPharmacologyAntitumor agentsbiologyDose-Response Relationship DrugMolecular StructureChemistryDrug Discovery3003 Pharmaceutical ScienceMedicine (all)Cell CycleOrganic ChemistryAntitumor agentG2/M phaseGeneral MedicineSettore CHIM/06 - Chimica OrganicaHeLa cell linebiology.organism_classificationSettore CHIM/08 - Chimica Farmaceuticamedicine.anatomical_structureCell cultureSettore CHIM/03 - Chimica Generale E InorganicathiophenesAntimitotic AgentTopoisomerase-II InhibitorDrug Screening Assays AntitumorHeLa CellsHuman
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¿Por qué Turismo? Repensar el auge del turismo

2017

In the present work we consider the reasons that explain the spectacular tourism boom in the last 5 decades. The traditional responses to this phenomenon, presented a whole "frond" of tourist-economical interactions: tourism as a "motor of development", tourism as "dynamizing the economic system", etc. Therefore, our objective is to contrast this Tourism-Development-Economic Growth framework, certainly suggestive. In order to avoid mystifications it is necessary to define somewhat ambiguous concepts such as Development (and its interactions with Tourism) and to deepen the economic impact of Tourism, the ultimate root of all that "frond" that seems to be the basis of This formidable theoreti…

torusim economic impact overtourism tourism industry local development innovationSettore SECS-P/06 - Economia Applicata
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Resurssiperustainen yritysyhteistyö pienten palveluyritysten verkostossa : tapaustutkimus matkailualan verkostosta

2013

tourism and hospitalityverkostotbusiness networksocial capitalyritysyhteistyöinterfirm cooperationverkostojohtaminenresourcesresurssitmatkailualasosiaalinen pääomayrityksetpalveluyritykset
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A New Spatial Shift‐Share Decomposition: An Application to Tourism Competitiveness in Italian Regions

2020

The paper proposes a new version of spatial shift-share decomposition to improve on the various approaches to conventional shift-share analysis found in the literature. The novelty of our proposal is that it enables researchers to assess spatial competitiveness effects controlling for the influence of industrial specialization at both regional and neighborhood level. This new version is applied to inbound tourism in Italian regions and enables us to identify the best and worst performers. Our empirical results identify favorable scenarios in some areas of the country, such as Sardinia as well as regional advantage in a sizeable number of well-known destinations.

tourism competitiveneGeographySpatial shiftItalian regionsGeography Planning and DevelopmentDecomposition (computer science)spatial shift-share analysiEconomic geographyTourismEarth-Surface ProcessesGeographical Analysis
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La competittività di una destinazione turistica

2013

Measuring destination competitiveness and identifying its determinants are strategic goals for pol-icy makers and tourism stakeholders. In order to do so, the availability of valid and reliable moni-toring tools is requested. In this context quantitative measurement tools, such as composite indi-cators, able to account for complexity and providing easily interpretable measures, represent a useful option. Nowadays composite indicators are commonly used for these aims but some criticism is suggested on how this happens. In this paper we provide some definitions of destination competitiveness and focus on related measurement approaches. In particular, supply-side competitiveness is distinguish…

tourism competitiveness composite indicators destination managmentgestione della destinazioneSettore SECS-S/05 - Statistica Socialecompetittività turistica indicatori composti
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POSITIONING ROMANIA AS A TOURISM DESTINATION BASED ON THE INFORMATION FROM ONLINE TRAVEL GUIDES

2014

Concerned with asserting itself as a unique tourism destination, Romania has spent time and money and has put a lot of hope in choosing its brand elements and secondary associations, forgetting that brands are not built only through advertising. The points of contact through which customers get to know a brand are various: observation and personal use, oral advocacy, interactions with Romania’s citizens, online and mobile experiences, etc. This paper aims to highlight the importance of Romania’s positioning statement, as a tourism destination, based on the information from major online international travel guides, and to argue the harmonization of this approach in differentiating the brand …

tourism destination positioning points-of-difference points-of-parity brandStudies in Business and Economics
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Tourism destination and the role of trust

2012

Tourism destinations increasingly pose new challenges to the organizational and management aspects of tourism. The non-cooperative behavior of some companies, the difficulties of sharing a system of values, the absence or inadequacy of destination managers keep some destinations off the map of growth that is sought for by the stakeholders and shareholders of a given resort. This difficulty seems to lie in the scarce knowledge of the system of relations existing between firms and their degree of cooperation. The application of Social Network Analysis (SNA) and some indicators for network analysis provides a clearer and more analytical map of the links between tourism businesses located withi…

tourism destination relationships business clusters Social Network Analysis (SNA)Settore SECS-P/06 - Economia Applicata
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Soluzioni smart per la fruizione del patrimonio culturale in siti UNESCO

2022

tourism destinationUNESCOvirtual spaceICTsmart cultural heritagecultural heritageWorld Heritage ListSmart Tourism TechnologieSettore M-GGR/01 - Geografiaimaginative geographiesmart solutiondestination image
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Destinazione turistica e networks interni ed esterni: il turismo relazionale

2022

The limitation in the relations between people caused by the pandemic today pushes more and more travellers in search of experiences and interactions with the territories, especially those excluded from the current production processes and the dominant market logic. In this context, the tourism of the roots or return tourism is motivated by a need to rediscover their origins, discover them, or trace them in places related to the history of travellers or their families. We, therefore, describe the main dimensions of the relationship tourism model so that it can be applied to root tourism.

tourism destinationroots tourisminternal and external networkenterprisesSettore SECS-P/06 - Economia Applicata
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